CD28 anticorps

N° du produit ABIN6936657

L’anticorps Souris Monoclonal anti-CD28 a été validé pour FACS, IF et Func. Il convient pour détecter CD28 dans des échantillons de Humain.

Aperçu rapide pour CD28 anticorps (ABIN6936657)

Antigène: CD28

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD28 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Clone: CB28

Détail du produit anti-CD28 anticorps

Specificité: Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. Itis the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human CD28 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Functional Studies (Order Ab without BSA & Azide), ,Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat cells.Human lymph nodes and tonsils.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur CD28

Antigène: CD28

Autre désignation: CD28

Sujet: T-cell-specific surface glycoprotein CD28, Tp44,CD28
Cellular localisation: Cell Surface

Poids moléculaire: 44kDa (monomer), 88kDa (dimer)

ID gène: 940, 591629

UniProt: P10747

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response